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Prices may varyHealth score is for adult use as intended, per the manufacturer's SDS. It does not model child ingestion, accidental spill cleanup, or off-label use. See the safety panel below for full hazard classification, and /disclaimer for the full editorial scope.
GHS hazard codes are quoted from the manufacturer’s Safety Data Sheet. PPE tiers below translate those codes and the listed ingredient chemistry; they are not CarCareTruth recommendations.
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Only when: splash risk
Translated from the manufacturer’s Safety Data Sheet, Section 8
SDS §2 classifies the product as not hazardous · no H318 or H319 at mixture level (H319 sits on the ZDDP ingredient only). SDS §8 calls for chemical splash goggles if a risk assessment indicates eye contact is possible. The situational tier reflects oil-change pour/drain splash risk, not a mixture-level eye-hazard classification.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
Only when: prolonged use
Beyond SDS: translated from the ingredient chemistry
SDS §2 has no mixture-level skin classification · H315 (skin irritation) appears at ingredient level on ZDDP (CAS 68649-42-3) only. SDS §4 notes prolonged contact may cause dryness of the skin; chemical-resistant gloves during drain handling address the ingredient-level irritant and used-oil contact pathway.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
Only when: in enclosed space · prolonged use
Translated from the manufacturer’s Safety Data Sheet, Section 8
SDS §8 calls for respiratory protection if a risk assessment indicates inhalation of contaminants is possible, and specifically requires it for large spills handled without adequate ventilation; SDS §8 also sets mist exposure limits (5 mg/m³ 8-hour TWA / 10 mg/m³ 15-minute STEL) 'under conditions which may generate mists.' SDS §2 classifies the product as not hazardous with no mixture-level inhalation H-code, and §11 notes only that prolonged inhalation of high concentrations may damage the respiratory system. This is a poorly-ventilated-garage / large-spill precaution, not a mixture-level inhalation hazard for routine pour-and-drain oil changes.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
No PPE specified in published sources for ventilation. Absence does not imply “not needed” — consult the full Safety Data Sheet.
PPE tiers translate the manufacturer’s SDS and U.S. regulatory standards. Not professional safety advice. How we report safety.
Scope of these PPE tiers. The tiers on this page translate the product's Safety Data Sheet where one is published, plus its ingredient chemistry, into a comparable rating. They describe a formulation, not a situation: a tier is not a safety determination for any specific user, task, quantity, or environment. The manufacturer's label and use instructions govern how the product is handled. Where the product is used at work, the employer's PPE program and hazard assessment under 29 CFR 1910.132 decide what protection is selected, not this page.
No warranties. CarCareTruth makes no warranties, express or implied, and expressly disclaims the implied warranties of merchantability and fitness for a particular purpose.
This product ranks #6 of 23 in Motor Oil.Three above it ↓
Last reviewed June 9, 2026
TL;DR API SP + ILSAC GF-6A with GM dexos1 Gen 3, Ford WSS-M2C946-B1, Stellantis MS-6395, and Honda HTO-06 OEM approvals · among the broadest coverage in a consumer full synthetic. The 25,000-mile label claim is aspirational: BITOG UOA data supports healthy oil at 12,000-15,000 miles on typical daily-driver use.
Full synthetic on a PAO Group IV plus Group III hydrogenated base stack, certified to API SP + ILSAC GF-6A. The product page lists dexos1 Gen 3, WSS-M2C946-B1, MS-6395, and HTO-06 · broader OEM coverage than most consumer synthetics. The 25k label is for normal (non-severe) service; community UOA threads cluster around 12k·15k with healthy TBN.
Best for 2020-2026 GM, Ford, Stellantis, and Honda/Acura owners whose engines specify 5W-30 and require one of those named approvals · Signature covers all four in one bottle. Skip if cost-per-quart matters most; conventional API SP at OEM intervals costs a fraction. Skip for pre-2010 flat-tappet engines where ZDDP loading outweighs GF-6A fuel-economy credits.
SDS §2 classifies this as not hazardous · no signal word, no mixture-level H-codes. H304 is waived via the CLP viscosity exemption (KV40 = 61.7 cSt). No Prop 65 warning on the product listing or in SDS §15. The SDS on file was last revised in 2019 · seven years old; H-codes here reflect that revision and may not capture additive changes since, and the API SP / GF-6A certification (launched May 2020) postdates the SDS. IARC classifies mineral oil mist from used-oil combustion byproducts as a Group 1 carcinogen based on occupational studies; minimize skin contact during oil changes. Used oil goes to collection · not down the drain. AutoZone, O'Reilly, and municipal hazardous-waste facilities accept it.
The 25,000-mile interval is AMSOIL's label claim for normal (non-severe) service. Community UOA data from BITOG (Bob Is The Oil Guy) forum threads consistently shows healthy TBN and low oxidation markers at 12,000-15,000 miles on typical daily-driver use, with several documented runs past 20,000 miles on highway-dominant driving. The oil is genuinely capable past 10,000 miles; the full 25,000 figure is achievable under favorable conditions but is not the median real-world result. AMSOIL recommends following the OEM drain interval for severe service.
Yes · AMSOIL lists GM dexos1 Gen 3 among the OEM approvals on the Signature Series product page. dexos1 Gen 3 is the current approval required for 2020+ GM gasoline vehicles. The product also lists Ford WSS-M2C946-B1, Stellantis MS-6395, and Honda HTO-06 approvals. Confirm the current OEM approval list on AMSOIL's product page before relying on this oil for warranty documentation.
API SP is the current top-tier gasoline engine oil specification through 2026, succeeding API SN Plus. ILSAC GF-6A adds fuel economy and chain-wear protection on top of API SP · required for most 2020+ gasoline passenger vehicles from Toyota, Honda, Ford, and GM. Using API SP + ILSAC GF-6A oil provides the deposit control, oxidation stability, and LSPI (low-speed pre-ignition) protection that older specs (API SN, SM) may not fully deliver for turbocharged or GDI engines.
Yes. SDS §3 confirms a base stock of Dec-1-ene homopolymer (PAO Group IV, 10-30%) and hydrogenated base oil (Group III, 10-30%) · a Group III + Group IV synthetic blend within the formulation, both classified as full synthetic under API base stock definitions. There is no Group I or Group II conventional content disclosed.
AMSOIL lists Honda/Acura HTO-06 among the approvals for Signature Series 5W-30. Honda Genuine Motor Oil is Honda's private-label product; any oil meeting the HTO-06 spec is functionally equivalent for warranty purposes in engines specifying a 5W-30 viscosity grade. HTO-06 on the 5W-30 grade does not substitute for applications requiring 0W-20 · viscosity-grade match is still required.
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