DMDM Hydantoin
- Other
- CAS 6440-58-0
- IUPAC: 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
DMDM Hydantoin is a formaldehyde-releasing preservative (biocide) used at trace concentrations (typically ≤ 0.003%) to prevent microbial growth in water-based formulas. It releases small amounts of formaldehyde as a byproduct of its antimicrobial mechanism. DMDM Hydantoin itself is not on the Prop 65 list (CAS 6440-58-0); formaldehyde (CAS 50-00-0) is listed separately but is only relevant at the concentrations where it is present — at ≤ 0.002% DMDM Hydantoin the released formaldehyde is far below any Prop 65 threshold. Not an asthmagen at these use concentrations; H334 respiratory sensitizer classification does not apply. At occupational concentrate levels (>0.1%) it can cause allergic skin reactions (H317 skin sensitizer) in sensitive individuals.
Health & environment profile
- VOC
- no
- Prop 65 listed
- no
- Asthmagen
- no
- EPA Safer Choice
- no
- Aquatic toxicity
- no
- Biodegradable
- yes
- Bioaccumulative
- no
- Persistent
- no
- Ozone depleting
- no
- Microplastic
- no
- PFAS
- no
- Env. score
- 4/5
3 products contain this

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Health summaries are editorial — we synthesize from SDSs, peer-reviewed sources, and regulatory listings. Not medical advice.