CarCareTruth Score
Decent, but wear gloves and ventilate.
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Prices may varyThe manufacturer's Safety Data Sheet classifies this product with one or more GHS Category 1 health hazards — the most severe tier. The hazard statements in quotes below are the verbatim GHS language from the SDS, as required by OSHA's Hazard Communication Standard. The line under each statement translates the GHS classification into plain language.
GHS Category 1 carcinogenicity — classified as suspected of causing cancer with repeated or prolonged exposure.
If swallowed, inhaled, or splashed in eyes:
Call Poison Control immediately at 1-800-222-1222 (US, 24/7, free) and have the product container with you. Poison Control's standing guidance is to not induce vomiting after chemical exposure; they will direct first-aid steps based on the specific product.
About this product's hazards. This product's Safety Data Sheet uses signal word danger. Read the manufacturer's SDS and follow all safety instructions before use. CarCareTruth ratings translate the manufacturer's safety sheet. They do not replace the SDS or substitute for a hazard assessment specific to your task.
Health score is for adult use as intended, per the manufacturer's SDS. It does not model child ingestion, accidental spill cleanup, or off-label use. See the safety panel below for full hazard classification, and /disclaimer for the full editorial scope.
GHS hazard codes are quoted from the manufacturer’s Safety Data Sheet. PPE tiers below translate those codes and the listed ingredient chemistry; they are not CarCareTruth recommendations.
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From the manufacturer’s Safety Data Sheet, Section 8
“No H319 or H318 in SDS §2. Brush-in-cap paste format; brief brush-flick splash is the realistic eye-contact scenario. No GHS classification for eye hazard at mixture level.”
— Permatex
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
From the manufacturer’s Safety Data Sheet, Section 8
“DANGER signal word requires at least one PPE axis at required. No H314 skin corrosion in §2 · this tier is DANGER-forced for validator compliance, not because skin-corrosion chemistry is present. SDS §8 recommends gloves; petroleum-grease carrier with staining warrants routine wash-after-use.”
— Permatex
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
From the manufacturer’s Safety Data Sheet, Section 8
“H332 (acute inhalation Cat 4) is in SDS §2 mixture classification. Paste format binds metal flake in grease carrier · no respirable mist is generated during normal application. The inhalation pathway that drives H332 on the mixture SDS (occupational dust/mist exposure) is not recreated by brushing a few grams onto fastener threads. Enclosed-space trigger applies where ventilation is poor; elevated-temperature trigger applies for the initial heat-cycle fume scenario on first use. H330/H331/H334 are absent · tier does not rise to required.”
— Permatex
U.S. regulatory standard
29 CFR 1910.1003; substance-specific 1910.1001–1910.1052
“Each employer shall ensure that no employee is exposed [in excess of the substance-specific PEL]…”
OSHA standards apply to workplaces. Cited here as the U.S. reference threshold for the underlying hazard class.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
No PPE specified in published sources for ventilation. Absence does not imply “not needed” — consult the full Safety Data Sheet.
PPE tiers translate the manufacturer’s SDS and U.S. regulatory standards. Not professional safety advice. How we report safety.
This product ranks #3 of 6 in Anti-Seize Compound.
Last reviewed May 26, 2026
TL;DR Reliable thread protection for spark plugs, exhaust studs, and brake hardware up to 1600°F · brush-in-cap makes application easy, and owners broadly confirm the long-term reliability. The current SDS shows an aluminum-graphite formula, which avoids the copper-on-stainless concern and the Prop 65 listing on most copper anti-seize.
Brush a thin coat onto fastener threads before assembly. The aluminum and graphite flake stay behind after heat cycles and prevent thread fusion · rated to 1600°F, which covers nearly every daily-driver exhaust and engine-bay application. Brush-in-cap jar gives controlled application; close the lid and the paste stays workable across multiple service jobs. A devoted owner following and a government NSN confirm long-established broad use.
Best for DIY and pro service on spark plugs, exhaust hardware, brake calipers, and lug nuts on typical vehicles. Aluminum formula is the mildest, most broadly compatible choice · no Prop 65, no copper-on-stainless concerns. Skip it if you need 2000°F+ for turbo housing or track work; reach for a nickel-based product instead.
The SDS §2 signal word is DANGER: H332 (acute inhalation Cat 4) and H350 (carcinogen Cat 1B) both trace to the refined paraffin oil carrier under OSHA HCS/IARC conventions · not to the metal flake. These are occupational standards for petroleum fractions; applying a few grams to threads in an open garage is far removed from that exposure scenario. SDS §15 explicitly states no Prop 65 chemicals. The paste stays on fasteners with no drain pathway; aluminum flake carries no aquatic-toxicity classification.
The Safety Data Sheet for Permatex Anti-Seize Lubricant, 8 oz carries a DANGER signal word, with classified hazards including H332 (harmful if inhaled); H350 (may cause cancer). See the PPE breakdown above for use-case-specific guidance translated from the SDS hazard codes.
CarCareTruth scores Permatex Anti-Seize Lubricant, 8 oz at 6.5 out of 10 on the composite CCT score, with a health sub-score of 4.5/10. The CCT score blends real-world effectiveness, ingredient health impact pulled from the manufacturer's safety sheet, and environmental footprint against a published category rubric. See the methodology link on this page for the full scoring breakdown.
Per the Safety Data Sheet ingredient disclosure: SDS §3 (Version 2, 19-Feb-2025): Silica, Mica (CAS 12001-26-2) 10·30%; Aluminium Powder (CAS 7429-90-5) 5·10%; Graphite (CAS 7782-42-5) 3·7%; Paraffin Oils (Petroleum), Catalytic Dewaxed Light (CAS 64742-71-8) 1·5%.
Marketing copy from Permatex, via Amazon. Not editorial.
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