CarCareTruth Score
Decent, but wear gloves and ventilate.
Opens Amazon in a new tab. No account needed to look.
Saved to your guest loadout. Sign up to also save to your Cabinet (consumables) or Kit (tools you own).
As an Amazon Associate I earn from qualifying purchases. Full disclosure
Prices may varyThe manufacturer's Safety Data Sheet classifies this product with one or more GHS Category 1 health hazards — the most severe tier. The hazard statements in quotes below are the verbatim GHS language from the SDS, as required by OSHA's Hazard Communication Standard. The line under each statement translates the GHS classification into plain language.
GHS Category 1 carcinogenicity — classified as suspected of causing cancer with repeated or prolonged exposure.
If swallowed, inhaled, or splashed in eyes:
Call Poison Control immediately at 1-800-222-1222 (US, 24/7, free) and have the product container with you. Poison Control's standing guidance is to not induce vomiting after chemical exposure; they will direct first-aid steps based on the specific product.
About this product's hazards. This product's Safety Data Sheet uses signal word danger. Read the manufacturer's SDS and follow all safety instructions before use. CarCareTruth ratings translate the manufacturer's safety sheet. They do not replace the SDS or substitute for a hazard assessment specific to your task.
Health score is for adult use as intended, per the manufacturer's SDS. It does not model child ingestion, accidental spill cleanup, or off-label use. See the safety panel below for full hazard classification, and /disclaimer for the full editorial scope.
GHS hazard codes are quoted from the manufacturer’s Safety Data Sheet. PPE tiers below translate those codes and the listed ingredient chemistry; they are not CarCareTruth recommendations.
Show details for all categories ▾Hide details ▴
From the manufacturer’s Safety Data Sheet, Section 8
“No H319 or H318 in SDS §2 mixture classification. Brush-flick splash is the realistic trigger during application of a sticky paste with a cap-integrated brush.”
— Permatex
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
From the manufacturer’s Safety Data Sheet, Section 8
“H317 skin sensitizer (nickel ≥5% in SDS §3) confirmed in SDS §2 mixture classification. Nickel is a well-documented Type IV delayed-hypersensitivity allergen. Mandatory for nickel-based anti-seize per rubric O-rule.”
— Permatex
U.S. regulatory standard
29 CFR 1910.138(a)
“appropriate hand protection when employees' hands are exposed to hazards such as those from… chemicals which produce an adverse effect on the skin or eyes…”
OSHA standards apply to workplaces. Cited here as the U.S. reference threshold for the underlying hazard class.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
From the manufacturer’s Safety Data Sheet, Section 8
“Paste format with no inhalation pathway during normal application · H372 STOT RE Cat 1 is the repeated-occupational-exposure classification, not a single-use application hazard. No H334/H335 in SDS §2. Elevated-temperature trigger applies when fastener heats on first cycle (thermal decomposition fumes possible in engine bay).”
— Permatex
U.S. regulatory standard
29 CFR 1910.1003; substance-specific 1910.1001–1910.1052
“Each employer shall ensure that no employee is exposed [in excess of the substance-specific PEL]…”
OSHA standards apply to workplaces. Cited here as the U.S. reference threshold for the underlying hazard class.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
No PPE specified in published sources for ventilation. Absence does not imply “not needed” — consult the full Safety Data Sheet.
PPE tiers translate the manufacturer’s SDS and U.S. regulatory standards. Not professional safety advice. How we report safety.
This product ranks #2 of 6 in Anti-Seize Compound.
Last reviewed May 26, 2026
TL;DR Nickel formula rated to 2400°F · the pick for stainless exhaust studs, titanium fasteners, and anywhere copper anti-seize risks stress-corrosion cracking. DANGER signal word is real chemistry, not flammability: H350 (carcinogen Cat 1B) and H372 (organ damage) at the §2 mixture level.
Nickel-based paste rated to 2400°F (TDS confirmed), OEM recommended for stainless, titanium, and nickel-alloy fasteners · exhaust studs, spark plug threads, O2 sensor bungs. Brush a thin coat on threads; the nickel-flake residue protects the joint after the carrier cooks off. Brush-top bottle gives controlled application. The owner review base is still modest, so treat the verdict as provisional, though early reports are uniformly positive. TDS note: not for wheel lug nuts or studs.
Best for stainless exhaust studs, titanium fasteners, and spark plugs in aluminum-head engines at high heat. Skip for general-purpose steel hardware · aluminum- or copper-based anti-seize scores better on health with adequate protection for those applications.
DANGER from health H-codes at SDS §2: H350 (carcinogen Cat 1B) and H372 (STOT RE Cat 1), both from nickel and petroleum-carrier chemistry. H317 nickel skin sensitizer in §2 · buyers with nickel allergy should choose aluminum-based anti-seize. SDS §15 lists nickel as a Prop 65 carcinogen; Amazon API false negative overridden. Gloves during application. Paste has no inhalation pathway under normal use; lung protection situational. VOC 0 g/L. Nickel is a CWA Priority Pollutant; petroleum carrier is non-biodegradable.
The Safety Data Sheet for Permatex 77124 Nickel Anti-Seize Lubricant carries a DANGER signal word, with classified hazards including H315 (causes skin irritation); H317 (may cause an allergic skin reaction); H350 (may cause cancer). The Amazon listing also carries a California Prop 65 warning. See the PPE breakdown above for use-case-specific guidance translated from the SDS hazard codes.
CarCareTruth scores Permatex 77124 Nickel Anti-Seize Lubricant at 6.6 out of 10 on the composite CCT score, with a health sub-score of 3.7/10. The CCT score blends real-world effectiveness, ingredient health impact pulled from the manufacturer's safety sheet, and environmental footprint against a published category rubric. See the methodology link on this page for the full scoring breakdown.
Per the Safety Data Sheet ingredient disclosure: SDS §3 (v7, 24-Feb-2020): Distillates (Petroleum), Solvent-Refined Heavy Naphthenic (CAS 64741-96-4) 50·75%; Graphite (CAS 7782-42-5) 10·30%; Nickel (CAS 7440-02-0) 5·10%; Aluminium Powder (CAS 7429-90-5) 1·5%.
Marketing copy from Permatex, via Amazon. Not editorial.
Weekly pick
One product, one safety verdict, every week. No spam.
Loctite
LB 8023 Marine Grade Anti-Seize
Loctite
LB 8008 C5-A Anti-Seize Lubricant
Never-Seez
NBBT-8 Blue Moly Anti-Seize Compound
As an Amazon Associate I earn from qualifying purchases. Full disclosure
Community
0 postsShare how you use this product
Drop a quick comment or post a full review with photos and a star rating.
Sign in to postNew here? Create a free account.