Permatex 77124 Nickel Anti-Seize Lubricant
Priced as of May 20, 2026
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Prices may varyAbout this product's hazards. This product's Safety Data Sheet uses signal word danger. Read the manufacturer's SDS and follow all safety instructions before use. CarCareTruth ratings translate SDS data — they do not replace the SDS or substitute for a hazard assessment specific to your task.
From the Safety Data Sheet
Full SDS ↗ (rev. 2020-02-24)GHS hazard codes are quoted from the manufacturer’s Safety Data Sheet. PPE tiers below translate those codes and the listed ingredient chemistry; they are not CarCareTruth recommendations.
EyesSituationalMfr. SDS §8SkinRequiredMfr. SDS §8 · 29 CFR 1910.138(a) · GHS H315LungsSituationalMfr. SDS §8 · 29 CFR 1910.1003 · GHS H350Ventilation—No PPE in published sourcesShow details for all categories ▾Hide details ▴
From the manufacturer’s Safety Data Sheet, Section 8
“No H319 or H318 in SDS §2 mixture classification. Brush-flick splash is the realistic trigger during application of a sticky paste with a cap-integrated brush.”
— Permatex
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
From the manufacturer’s Safety Data Sheet, Section 8
“H317 skin sensitizer (nickel ≥5% in SDS §3) confirmed in SDS §2 mixture classification. Nickel is a well-documented Type IV delayed-hypersensitivity allergen. Mandatory for nickel-based anti-seize per rubric O-rule.”
— Permatex
U.S. regulatory standard
29 CFR 1910.138(a)
“appropriate hand protection when employees' hands are exposed to hazards such as those from… chemicals which produce an adverse effect on the skin or eyes…”
OSHA standards apply to workplaces. Cited here as the U.S. reference threshold for the underlying hazard class.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
From the manufacturer’s Safety Data Sheet, Section 8
“Paste format with no inhalation pathway during normal application — H372 STOT RE Cat 1 is the repeated-occupational-exposure classification, not a single-use application hazard. No H334/H335 in SDS §2. Elevated-temperature trigger applies when fastener heats on first cycle (thermal decomposition fumes possible in engine bay).”
— Permatex
U.S. regulatory standard
29 CFR 1910.1003; substance-specific 1910.1001–1910.1052
“Each employer shall ensure that no employee is exposed [in excess of the substance-specific PEL]…”
OSHA standards apply to workplaces. Cited here as the U.S. reference threshold for the underlying hazard class.
CarCareTruth publishes the cited sources verbatim and does not advise what action a user should take. Consult the full SDS before use.
No PPE specified in published sources for ventilation. Absence does not imply “not needed” — consult the full Safety Data Sheet.
PPE tiers translate the manufacturer’s SDS and U.S. regulatory standards. Not professional safety advice. How we report safety.
CarCareTruth's Analysis
Last reviewed May 20, 2026
TL;DR Nickel formula rated to 2400°F — the pick for stainless exhaust studs, titanium fasteners, and anywhere copper anti-seize risks stress-corrosion cracking. DANGER signal word is real chemistry, not flammability: H350 (carcinogen Cat 1B) and H372 (organ damage) at the §2 mixture level.
What it is and how it performs
Nickel-based paste rated to 2400°F (TDS confirmed), OEM recommended for stainless, titanium, and nickel-alloy fasteners — exhaust studs, spark plug threads, O2 sensor bungs. Brush a thin coat on threads; the nickel-flake residue protects the joint after the carrier cooks off. Brush-top bottle gives controlled application. Amazon verified-purchase reviewers (4.7★, 6 ratings) are few but uniformly positive. TDS note: not for wheel lug nuts or studs.
Who should buy this — and who should skip it
Best for stainless exhaust studs, titanium fasteners, and spark plugs in aluminum-head engines at high heat. Skip for general-purpose steel hardware — aluminum- or copper-based anti-seize scores better on health with adequate protection for those applications.
Safety and environmental impact
DANGER from health H-codes at SDS §2: H350 (carcinogen Cat 1B) and H372 (STOT RE Cat 1), both from nickel and petroleum-carrier chemistry. H317 nickel skin sensitizer in §2 — buyers with nickel allergy should choose aluminum-based anti-seize. SDS §15 lists nickel as a Prop 65 carcinogen; Amazon API false negative overridden. Gloves during application. Paste has no inhalation pathway under normal use; lung protection situational. VOC 0 g/L. Nickel is a CWA Priority Pollutant; petroleum carrier is non-biodegradable.
From the manufacturer
Marketing copy from Permatex, via Amazon. Not editorial.
- •Permatex
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Manufacturer specifications
- Material
- Copper,Metal,Stainless Steel
- Brand
- Permatex
- Package Information
- Bottle
- Liquid Volume
- 8 Fluid Ounces
- Item Weight
- 8 Ounces
- Brand Name
- Permatex
- Recommended Uses For Product
- Fleet and plant maintenance.
- Specific Uses For Product
- Fleet and plant maintenance.
- Item Form
- Liquid
- Manufacturer
- Permatex
- Unit Count
- 1.0 Count
- Number of Items
- 1
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