WIX Filters 49350 Engine Air Filter
Priced as of May 14, 2026
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Prices may varyCarCareTruth's Analysis
Last reviewed May 15, 2026
TL;DR Disposable pleated-paper OEM replacement made by MANN+HUMMEL (the Tier 1 OEM filtration supplier behind the WIX and NAPA Gold brands) with a drop-in fit confirmed for the 2010–2024 Toyota 4Runner 4.0L V6. The ≥99% ISO 5011 filtration efficiency figure is manufacturer-published — no independent consumer-lab test exists for this specific SKU, which keeps the score honest rather than exceptional.
What it is and how it performs
The WIX 49350 is a disposable pleated-paper filter using phenolic-resin-treated cellulose media with pleat stabilization beads — the same construction Toyota specifies as OEM. WIX is manufactured by MANN+HUMMEL, a Tier 1 OEM supplier, which is why the filtration efficiency claim (≥99% at ISO 5011 medium test dust) carries more credibility than a typical aftermarket marketing assertion; MANN+HUMMEL publishes this data in the context of genuine OEM supply relationships. No independent consumer-lab test for this specific retail SKU exists in the reviewed evidence base. The OEM cross-reference to Toyota 17801-0W010 is confirmed across RockAuto, AutoZone, and NAPA; multiple community reviews spanning 2010 through 2023 4Runner model years confirm drop-in fit and a solid seal in the factory air box. Replacement interval follows Toyota's OEM recommendation: 15,000–30,000 miles depending on duty cycle.
Who should buy this — and who should skip it
Right pick for a 5th gen Toyota 4Runner, Lexus GX460, or FJ Cruiser owner who wants an OEM-quality replacement at below-dealer pricing — the filter's manufacturer (MANN+HUMMEL) supplies the OEM production line for the same platform. Skip if your 4Runner is a 6th generation (2025+) — the newly redesigned platform uses a different engine and air box; verify the part number against your specific model year. Also skip if you're switching from a K&N washable filter and prioritizing long-term cost savings over replacement cycles — a washable reusable filter eliminates the disposable replacement cadence entirely, though at a higher upfront cost.
Safety and environmental impact
Passive replacement component — no chemical exposure pathway during installation or removal; no SDS applies. Environment score of 4, reflecting a standard disposable filter lifecycle: a single-use paper-and-cardboard unit replaced on the OEM 15,000–30,000 mile service interval, with composite construction (cellulose media, cardboard frame, polyurethane foam seal) that goes to landfill at replacement with limited municipal recyclability.
Frequently asked questions
Does the WIX 49350 fit the 5th gen Toyota 4Runner?▾
Yes — the WIX 49350 is confirmed for the Toyota 4Runner 2010–2024 (4.0L V6, 5th generation). It cross-references to OEM Toyota part 17801-0W010 and is verified against RockAuto, AutoZone, and NAPA application databases. Community reviews for 2010 through 2023 model years confirm drop-in fit in the air box. Always verify with your specific year, make, model, and engine before purchase.
Does the WIX 49350 fit the Lexus GX460?▾
Yes — the WIX 49350 also fits the Lexus GX460 2010–2023. The GX460 shares the 4.0L V6 engine and air box design with the 5th gen 4Runner.
Is WIX an OEM-grade filter brand?▾
WIX is owned by MANN+HUMMEL Group, a Tier 1 OEM filtration supplier that manufactures filters for multiple vehicle manufacturers. WIX and NAPA Gold filters are made by the same manufacturer — WIX makes NAPA Gold equivalents as part of the same production line.
What is the replacement interval for the WIX 49350?▾
Toyota specifies 15,000–30,000 miles depending on driving conditions — lighter-duty highway driving can reach the longer end; dusty or off-road conditions warrant the shorter interval. WIX defers to the OEM recommendation. Check your owner's manual for the specification for your driving conditions.
From the manufacturer
Marketing copy from WIX Filters, via Amazon. Not editorial.
- •PREMIUM ENGINE PROTECTION: WIX Air Filters keep harmful dust away from engine internals and from getting suspended in the engine's lubricating oil
- •PRECISE, ACCURATE SEAL: Constructed with heat-resistant plastisol with specially designed, pliable seals on the top and bottom walls
- •PERFORMANCE AND DURABILITY: Embossed pleats and pleat stabilization beads help the filter trap more dirt, helping engines achieve maximum performance and last longer
- •MAINTENANCE: Engine air filters are critical to the life of an engine and should be regularly replaced as a part of routine maintenance; Refer to your owner's manual for the appropriate service interval
- •COMPATIBILITY NOTE: Verify vehicle fitment by entering vehicle information in the part finder stripe to ensure this is the correct filter for your vehicle
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Manufacturer images

Manufacturer specifications
- Product Grade
- Replacement Part
- Brand
- Wix
- Fit Type
- Vehicle Specific Fit
- Product Dimensions
- 13.25"L x 13.25"W x 9.29"H
- OEM Part Number
- 49350
- Brand Name
- Wix
- Model Number
- 49350
- OEM Equivalent Part Number
- 49350
- Manufacturer Part Number
- 49350
- Global Trade Identification Number
- 00765809493506
- Manufacturer
- WIX
- UPC
- 765809493506
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