Lauramine Oxide
- Amphoteric surfactants
- CAS 1643-20-5
- IUPAC: N,N-Dimethyldodecan-1-amine oxide
Lauramine Oxide (CAS 1643-20-5) appears in 9 of the 2,122 car-care products CarCareTruth tracks (as of August 2026). It is on the EPA Safer Choice list.
May cause eye and skin irritation at concentrate strength; supplier SDS data for the neat substance also documents H318 (serious eye damage) and H302 (harmful if swallowed) at full concentration, a more severe profile than 'minimal irritation potential' implies. At typical consumer product concentrations (well under 5%), irritation potential is substantially reduced. No sensitization, no mutagenicity, no carcinogenicity (not IARC-, NTP-, or OSHA-Ca-listed). NFPA Health rating on supplier SDS for the neat substance is 3 (serious hazard), not 1; a prior version of this file understated this.
Lauramine oxide (also known as lauryldimethylamine oxide or LDAO) is an amphoteric surfactant used as a foam booster, viscosity builder, and co-surfactant in cleaning formulations. It functions synergistically with anionic surfactants like SLS to enhance foam density and cleaning performance.
Readily biodegradable. Not on Prop 65, not an asthmagen, not a sensitizer, not a carcinogen. At typical consumer product concentrations (often under 5%), acute health irritation potential is low. Aquatic toxicity, however, is a real and confirmed hazard for the pure substance: multiple independent supplier SDS documents classify CAS 1643-20-5 as Aquatic Acute 1 (H400, "very toxic to aquatic life") and Aquatic Chronic 1 (H410, "very toxic to aquatic life with long lasting effects"), carrying the GHS09 environmental pictogram. A prior version of this file stated aquatic_toxicity: false and described the aquatic profile as benign; that was incorrect and is corrected here.
Regulatory status / hazard corrections
- Not California Prop 65 listed, not IARC/NTP/OSHA-Ca carcinogen-listed. These parts of the prior file's summary were accurate and are unchanged.
aquatic_toxicitycorrected fromfalsetotrue. This file previously described the aquatic profile as "low... well below 1%" and claimed "no bioaccumulation potential." Both understated the hazard: the neat substance is classified Aquatic Acute 1 / Chronic 1 (the most severe GHS aquatic tiers), and while a low estimated bioconcentration factor (BCF approximately 0.7, suggesting low bioaccumulation potential specifically) is separately documented, that is a different axis from acute/chronic aquatic toxicity and does not offset it.- The NFPA Health rating for the neat substance is 3 ("serious hazard"), not 1 ("slight hazard") as the prior file stated.
Sources
- Cayman Chemical SDS for LDAO (Lauramine Oxide, CAS 1643-20-5), revision 2026-01-07: GHS classification includes Eye damage 1 (H318), Acute toxicity oral 4 (H302), Skin irritation 2 (H315), Aquatic Acute 1 (H400), Aquatic Chronic 1 (H410); pictograms GHS05, GHS07, GHS09; signal word DANGER; NFPA Health 3 / Fire 0 / Reactivity 0; SDS §12 remark "Very toxic for fish," Water hazard class 3 ("extremely hazardous for water"). Not IARC-, NTP-, or OSHA-Ca-listed; not SARA 313; TSCA active.
- Independent corroboration:
content/products/sun-joe/sun-joe-snow-foam-car-wash-soap-coconut/notes.mddocuments this same discrepancy from a second, independent primary source, that product's own SDS §3, which discloses lauramine oxide under the supplier trade name "Mazox CG" (Mason Chemical Company) at CAS 1643-20-5 and classifies it ingredient-level Aquatic Acute 1 (H400) / Aquatic Chronic 1 (H410), matching the Cayman Chemical SDS exactly. That build did not edit this shared file at the time; it scored the product directly from its own SDS finding and left a note for "the ingredient-file owner to reconcile in a future pass." This correction is that reconciliation. - Blast-radius note (environment axis, ingredient-level aquatic-toxicity stacking rule, -1.0 raw per flagged ingredient, capped at -2.0 raw, multiplied by the product's exposure-pathway factor): this correction was NOT accompanied by edits to any consuming product file, per this audit's file-ownership scope (product files are owned by another process). See the audit report for the full per-product blast-radius accounting; in summary, several products already independently scored lauramine oxide's real aquatic toxicity from their own SDS (no change on next regen), several are already at the -2.0 ingredient-level cap from other aquatic-toxic ingredients (no change), and several currently show an explicit "lauramine-oxide: aquatic_toxicity: false, no deduction" citation that would need to become a real deduction on their next regen.
Health & environment profile
- VOC
- no
- Prop 65 listed
- no
- Asthmagen
- no
- EPA Safer Choice
- yes
- Aquatic toxicity
- yes
- Biodegradable
- yes
- Bioaccumulative
- no
- Persistent
- no
- Ozone depleting
- no
- Microplastic
- no
- PFAS
- no
- Env. score
- 2/5
Common questions about Lauramine Oxide
- What is Lauramine Oxide used for in car care?
- Amphoteric surfactant — foam booster, viscosity modifier, and co-surfactant in cleaning products
- Is Lauramine Oxide a VOC?
- No. Lauramine Oxide is not classified as a volatile organic compound (VOC).
- Is Lauramine Oxide on California's Proposition 65 list?
- No. Lauramine Oxide is not on California's Proposition 65 list.
- Is Lauramine Oxide EPA Safer Choice certified?
- Yes. Lauramine Oxide is on the EPA Safer Choice list.
9 products contain this
P&S Detail Products Pearl Auto Shampoocar-shampoo
P&S Detail Products Xpress Interior CleanerProp 65plastic-trim-cleaner
Rocco & Roxie Carpet Cleaner Solution for Petsextractor-solution

Turtle Wax ICE Snow Foam Car Washcar-shampoo
Turtle Wax Power Out! Carpet & Mats Heavy Duty Cleanercarpet-cleaner
Turtle Wax Power Out! Upholstery Cleaner Odor Eliminatorheadliner-cleaner
Turtle Wax Spot Clean Stain & Odor RemoverProp 65fabric-upholstery-cleaner
Windex Automotive Glass Cleanerglass-cleaner
Related
Health and environment notes translate the manufacturer Safety Data Sheet, the GHS classification, and authoritative regulatory listings (California Prop 65, EPA). Not medical advice. They describe the ingredient itself; whether a hazard applies to a finished product depends on its concentration and how it's used.