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Dipropylene Glycol Monomethyl Ether

  • Glycol ether solvents
  • CAS 34590-94-8
  • IUPAC: 1-methoxy-2-(2-methoxypropoxy)propane

H227 (combustible liquid) is the only GHS classification. Low acute toxicity by all routes. No skin sensitization, carcinogenicity, or reproductive toxicity concerns. Safe at typical 1–30% product concentrations with normal handling.

Dipropylene glycol monomethyl ether (DPGME, Dowanol DPM) is a glycol ether solvent widely used in water-based automotive cleaners, dressings, and coatings. It functions as a coupling agent that enables stable emulsions of water-soluble and oil-soluble ingredients. DPGME has an excellent safety profile compared to other glycol ethers: it does not cross the blood-brain barrier, does not cause reproductive toxicity, and is not classified as a carcinogen or skin sensitizer. The H227 classification (combustible liquid, flash point ~75°C) is the only GHS hazard. At typical product concentrations of 1–30%, DPGME poses minimal health risk for normal detailing use.

Health & environment profile

VOC
yes
Prop 65 listed
no
Asthmagen
no
EPA Safer Choice
no
Aquatic toxicity
no
Biodegradable
yes
Bioaccumulative
no
Persistent
no
Ozone depleting
no
Microplastic
no
PFAS
no
Env. score
4/5
Purpose: Coupling agent; helps water-soluble and oil-soluble ingredients coexist in a single aqueous formulation

4 products contain this

Health summaries are editorial — we synthesize from SDSs, peer-reviewed sources, and regulatory listings. Not medical advice.