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1-Methoxy-2-propyl Acetate

  • Esters
  • CAS 108-65-6
  • IUPAC: 1-methoxypropan-2-yl acetate

1-Methoxy-2-propyl Acetate (CAS 108-65-6) appears in 1 of the 1,812 car-care products CarCareTruth tracks (as of June 2026). It is classified as a VOC.

Low acute toxicity. GHS classification: may cause drowsiness or dizziness (H336) at high vapor concentrations. Not Prop 65–listed. Not an asthmagen. Vapors should be controlled in enclosed spaces.

1-Methoxy-2-propyl acetate (also known as propylene glycol monomethyl ether acetate, PGMEA) is a co-solvent ester used in paints, lacquers, and coatings to slow evaporation rate relative to fast-evaporating solvents like acetone, improving film formation and leveling. It is a regulated VOC that contributes to ground-level ozone formation. Acute health risks at typical consumer exposure levels are low, though vapor control in enclosed spaces is appropriate.

Health & environment profile

VOC
yes
Prop 65 listed
no
Asthmagen
no
EPA Safer Choice
no
Aquatic toxicity
no
Biodegradable
yes
Bioaccumulative
no
Persistent
no
Ozone depleting
no
Microplastic
no
PFAS
no
Env. score
3/5
Purpose: Co-solvent in paints, coatings, and lacquers; moderates evaporation rate and aids film formation

Common questions about 1-Methoxy-2-propyl Acetate

What is 1-Methoxy-2-propyl Acetate used for in car care?
Co-solvent in paints, coatings, and lacquers; moderates evaporation rate and aids film formation
Is 1-Methoxy-2-propyl Acetate a VOC?
Yes. 1-Methoxy-2-propyl Acetate is classified as a volatile organic compound (VOC).
Is 1-Methoxy-2-propyl Acetate on California's Proposition 65 list?
No. 1-Methoxy-2-propyl Acetate is not on California's Proposition 65 list.
Is 1-Methoxy-2-propyl Acetate biodegradable?
Yes. 1-Methoxy-2-propyl Acetate has a confirmed biodegradable profile.

1 product contain this

Related

Health and environment notes translate the manufacturer Safety Data Sheet, the GHS classification, and authoritative regulatory listings (California Prop 65, EPA). Not medical advice. They describe the ingredient itself; whether a hazard applies to a finished product depends on its concentration and how it's used.