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1,4-Dioxane

  • Other solvents
  • CAS 123-91-1
  • IUPAC: 1,4-Dioxane
1,4-Dioxane is a probable human carcinogen (IARC Group 2B, EPA Class B2) found as a trace contaminant in products that use ethoxylated surfactants. It is not an intentional ingredient — it forms as a byproduct during the ethoxylation process. California Proposition 65 lists 1,4-dioxane as a known carcinogen. At trace concentrations typical in consumer detailing products, exposure risk from skin contact or inhalation during normal use is generally considered low, but the presence of a Prop 65 carcinogen triggers the required California warning label. EPA has been tightening drinking water guidance on 1,4-dioxane due to its groundwater persistence.

Health & environment profile

VOC
no
Prop 65 listed
yes
Asthmagen
no
EPA Safer Choice
no
Aquatic toxicity
no
Biodegradable
no
Bioaccumulative
no
Persistent
yes
Ozone depleting
no
Microplastic
no
PFAS
no
Env. score
2/5
Purpose: Process contaminant / trace impurity — not an intentional ingredient; forms as a byproduct during ethoxylation of surfactants (e.g., sodium laureth sulfate, polyethylene glycols)

1 product contain this

Health summaries are editorial — we synthesize from SDSs, peer-reviewed sources, and regulatory listings. Not medical advice.