Nonylphenol ethoxylate (NPE)
- Nonionic surfactants
- CAS 127087-87-0
Nonylphenol ethoxylate (NPE) (CAS 127087-87-0) appears in 1 of the 2,122 car-care products CarCareTruth tracks (as of August 2026).
Surfactant with no Prop 65 listing and no mixture-level GHS health classification at consumer concentrations. Direct contact with the concentrate can cause skin and eye irritation. The primary concern for this ingredient is environmental (aquatic toxicity and persistent breakdown products), not acute consumer health at the low use concentration.
What it is
Nonylphenol ethoxylate (NPE) is a nonionic surfactant made by reacting nonylphenol with ethylene oxide. It is a workhorse detergent and wetting agent that was used across household and industrial cleaners for decades because it is cheap and effective at cutting oily soils.
Where it appears in car care
NPE shows up in older or value-oriented cleaning formulations, including some glass and all-purpose cleaners, as the surfactant that provides detergency and sheeting. Newer formulas increasingly substitute alcohol ethoxylates or alkyl polyglucosides because those have a cleaner environmental profile.
Why it is flagged
The environmental record is the issue. NPE and its degradation product nonylphenol are toxic to aquatic organisms and are persistent and endocrine-active in the environment. The European Union restricts nonylphenol ethoxylates in detergents, and EPA's Safer Choice program steers formulators away from the class. In a wipe-off glass cleaner, residue reaches wastewater through cloth laundering, so the aquatic-toxicity flag is the relevant environmental pathway even at low product concentration.
Health & environment profile
- VOC
- no
- Prop 65 listed
- no
- Asthmagen
- no
- EPA Safer Choice
- no
- Aquatic toxicity
- yes
- Biodegradable
- no
- Bioaccumulative
- no
- Persistent
- yes
- Ozone depleting
- no
- Microplastic
- no
- PFAS
- no
- Env. score
- 2/5
Common questions about Nonylphenol ethoxylate (NPE)
- What is Nonylphenol ethoxylate (NPE) used for in car care?
- Nonionic surfactant and wetting/detergency agent used in cleaning formulations at low concentrations
- Is Nonylphenol ethoxylate (NPE) a VOC?
- No. Nonylphenol ethoxylate (NPE) is not classified as a volatile organic compound (VOC).
- Is Nonylphenol ethoxylate (NPE) on California's Proposition 65 list?
- No. Nonylphenol ethoxylate (NPE) is not on California's Proposition 65 list.
1 product contain this
Magic Finish Car Glass CleanerProp 65glass-cleaner
Related
Health and environment notes translate the manufacturer Safety Data Sheet, the GHS classification, and authoritative regulatory listings (California Prop 65, EPA). Not medical advice. They describe the ingredient itself; whether a hazard applies to a finished product depends on its concentration and how it's used.